💉 GLP-1 Injections & Constipation: Causes & Relief Tips

Managing a Common Side Effect of Popular Weight Loss Medications

If you’re receiving GLP-1 injections (like Wegovy, Ozempic, or compounded versions) for weight loss or diabetes, you may be experiencing a frustrating side effect: constipation. You're not alone—digestive slowdowns are one of the most common complaints with these medications.

At Florida Primary Care Center, we help patients succeed on their GLP-1 journey by offering expert guidance and personalized care for managing side effects like constipation. Here's why it happens—and how you can get relief naturally.

🧬 Why Do GLP-1 Injections Cause Constipation?

GLP-1 receptor agonists work by mimicking a natural hormone that helps regulate appetite, slow digestion, and stabilize blood sugar. That slowing of your digestive system is part of how the medication helps with weight loss—but it can also reduce gut motility, leading to:

• Infrequent bowel movements

• Hard, dry stools

• Bloating and abdominal discomfort

Constipation is especially common when appetite is reduced, fiber intake drops, or hydration levels fall after starting the injections.

🚨 Common Signs of GLP-1 Injections & Constipation

• Fewer than 3 bowel movements per week

• Painful, hard-to-pass stools

• Feeling bloated or sluggish

• Nausea or loss of appetite due to slow digestion

💡 Relief Tips for Constipation Caused by GLP-1 Injections

Here are our top, patient-tested strategies to stay regular while continuing your GLP-1 treatment:

1. 💧 Stay Well Hydrated

Appetite suppression often leads to reduced fluid intake. Aim for:

• 64–100 oz of water per day

• Consider electrolyte-enhanced water or adding lemon/lime

2. 🥦 Increase Fiber Slowly

Both soluble and insoluble fiber are key. Try:

• Chia seeds, flaxseed, berries, leafy greens, lentils

• Oatmeal, avocado, and fiber supplements like psyllium husk

Start small and build up to 25–35g of fiber daily to avoid bloating.

3. 🏃‍♀️ Move Daily

Physical activity promotes regularity:

• 15–30 minute walk

• Gentle yoga or stretching

• Try Hypervibe vibration therapy in-office to support lymph flow and bowel movement

4. 💊 Use Safe, Short-Term Supplements

Ask your provider about:

• Magnesium citrate or glycinate (natural stool softeners)

• Docusate sodium (Colace)

• Herbal teas like senna—for occasional use only

We also offer gut support supplement bundles through Fullscript that are GLP-1–friendly.

5. 📅 Create a Bowel Routine

Try to go at the same time daily, ideally after a meal. A predictable routine helps retrain your digestive system while your body adjusts to GLP-1.

🩺 When to Call Us

Reach out to your provider if you experience:

• No bowel movement for 5+ days

• Severe bloating or cramping

• Vomiting or nausea that doesn't resolve

• Blood or black stools

We’ll adjust your care plan and help you feel better—without interrupting your progress.

🧠 Final Thoughts

Constipation is a common side effect of GLP-1 injections, but it's usually temporary and treatable. With the right hydration, fiber, and guidance, you can stay regular and stay on track with your health goals.